Scientists Might Have Discovered A Crohn’s Disease Cure : uproxx

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Scientists Might Have Discovered A Crohn's Disease Cure

Scientists Might Have Discovered A Crohn's Disease Cure

Crohn's Disease is a legendarily difficult disease to not only identify but to treat or cure.The disease affects the intestines and digestive tract, stemming from bacteria in those areas building up and leading to serious side effects.It affects more than half a million people in the United States and is brutal – with the possibility of diarrhea, weight loss, fatigue, ulcers, malnutrition, and eventually colon cancer, liver disease or osteoporosis.Treatment is limited, with the current best options being medicine to limit inflammation and prevent symptoms.


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Fungi Has Its Own Role in Crohn's Disease

Fungi Has Its Own Role in Crohn's Disease

Recent research on Crohn's disease has focused a lot on bacteria, but a new study has concluded that fungus is a factor in developing the inflammatory bowel disease.Researchers from Case Western Reserve University School of Medicine led a study that evaluated patients with the disease, as well as their disease-free relatives.They looked at both bacteria and fungi from fecal samples.In doing so, they found a strong interaction between two bacteria and one fungus in sick family members.


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Researchers Make Discovery In Cause Of Crohn's Disease « CBS Miami

Researchers Make Discovery In Cause Of Crohn's Disease « CBS Miami

Follow CBSMIAMI.COM: Facebook | TwitterCLEVELAND (CBSMiami) – Researchers have made a breakthrough in the cause of Crohn's disease, which in turn, could lead to a cure.According to a new study, researchers at Case Western Reserve University identified a fungus that works with two types of bacteria to cause symptoms of Crohn's disease.The study is the first to find a fungus plays a role in development of the disease, and the discovery may lead to new ways of treating Crohn's, according to researchers involved with the study.Crohn's disease is an inflammatory bowel disorder that causes inflammation of the digestive tract leading to abdominal pain, severe diarrhea and fatigue, and is one of the most common forms of inflammatory bowel disorder.


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Bacteriome and Mycobiome Interactions Underscore Microbial Dysbiosis in Familial Crohn's Disease

Bacteriome and Mycobiome Interactions Underscore Microbial Dysbiosis in Familial Crohn's Disease

ABSTRACTCrohn's disease (CD) results from a complex interplay between host genetic factors and endogenous microbial communities.In the current study, we used Ion Torrent sequencing to characterize the gut bacterial microbiota (bacteriome) and fungal community (mycobiome) in patients with CD and their nondiseased first-degree relatives (NCDR) in 9 familial clusters living in northern France-Belgium and in healthy individuals from 4 families living in the same area (non-CD unrelated [NCDU]).Principal component, diversity, and abundance analyses were conducted, and CD-associated inter- and intrakingdom microbial correlations were determined.Significant microbial interactions were identified and validated using single- and mixed-species biofilms.