Record $75 million grant awarded for coronary heart disease research : cardiovascularbusiness

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Record $75 million grant awarded for coronary heart disease research

Record $75 million grant awarded for coronary heart disease research

A research team led by Calum MacRae, MD, chief of cardiovascular medicine at Brigham and Women's Hospital in Boston, received a $75 million grant to support his five-year research project to better understand coronary heart disease.The American Heart Association (AHA), Verily Life Sciences and AstraZeneca announced on Oct. 5 that MacRae and his team had won the One Brave Idea research award."One Brave Idea for me is a complete game-changer," MacRae said in a YouTube video."It's a totally different way of thinking about the direction and the scale of the funding that's available to move ideas forward in biomedical science."MacRae and his team plan on collecting genomic information, lifestyle data, public health data and responses from people with coronary heart disease in their families.


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Many ways to lower cholesterol will reduce heart disease risk

Many ways to lower cholesterol will reduce heart disease risk

Several contemporary clinical trials have shown that cholesterol-lowering statin drugs reduce the risk of heart attacks in patients with coronary artery disease.This compelling body of evidence has led to the question of whether other drugs that lower cholesterol also reduce heart attacks.Older studies had certainly shown this, though these studies were from an era prior to widespread statin use.A recent study showed that in patients with a mild heart attack, adding ezetimibe — a drug that interferes with cholesterol absorption from the intestines — to a statin reduced cardiovascular risk compared with a statin alone.


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Brigham doc wins $75m heart disease research grant – MassDevice

Brigham doc wins $75m heart disease research grant – MassDevice

Boston-based Brigham and Women's Hospital cardiovascular medicine chief Dr. Calum MacRae won a $75 million heart disease research grant from the American Heart Association to investigate coronary heart disease.The money comes from the One Brave Idea research grant, which was funded by the AHA, Verily Life Sciences and AstraZeneca (NYSE:AZN), with an eventual end goal of finding a cure for coronary heart disease and its consequences."After launching a global search effort earlier this year, we are proud to announce the selection of Dr. Calum MacRae as the leader of our One Brave Idea initiative.Dr. MacRae and his newly-formed, world-renowned, multidisciplinary team were selected from among hundreds of applicants throughout the world to receive this landmark award that will provide support over a five-year period for a research project focused on uncovering the causes of heart disease, including previously unrecognized signals marking the transition from wellness to the earliest, yet still largely invisible stages of disease," AHA CEO Nancy Brown said in a prepared release.