Study finds obesity may reprogram muscle stem cells
Epigenetic changes affect the formation of new muscle cells and may be a contributing factor to reduced muscle mass and impaired metabolism found in obesity. The study, led by Cajsa Davegardh, a doctoral student at Lund University, compared DNA methylation in muscle stem cells in obese and non-obese people. Results showed the pro-inflammatory gene IL-32 played a vital role in gene maturation and insulin sensitivity in fully mature muscle cells. "We believe that in obese individuals the muscle stem cells have been reprogrammed, and that this may partly explain why muscle cells in obese people have decreased insulin sensitivity and lower metabolism after they have matured," Davegardh said. Impairment of insulin sensitivity is common in obesity and type 2 diabetes.Mediterranean diet may decrease pain associated with obesity Those who eat more fish, plant proteins less likely to suffer, study findsCOLUMBUS, Ohio – Eating a Mediterranean diet could decrease the chances an overweight person will experience regular pain, new research suggests. And they tested the model using three different measures of weight – body mass index, waist circumference and body fat percentage. Eating more fish and plant-based proteins such as nuts and beans was linked with less pain, regardless of body weight. The pain evaluation provides an indicator of pain experienced during the previous month, but does not account for chronic pain of a longer duration. Emery said his next step is to examine body fat and pain using biomarkers associated with inflammation.
collected by :Lucy William
No comments:
Post a Comment