The signs of heart disease according to : Baltimore Sun

Cardiovascular disease or heart disease is a broad term that refers to several different types of issues an individual may have with their heart. The sudden death is the result of a heart attack that causes a lethal heart rhythm abnormality, known as ventricular fibrillation. Most people have some risk of heart disease: It is the leading cause of death in the United States. A heart attack occurs when the blood flow to a part of the heart is blocked by a blood clot. The first symptom of undiagnosed coronary disease is sudden death in almost one-third of patients with the disease.




The next step would be to develop a test that added mutations in CDH2 to the others known to be linked to heart conditions, Shaboodien said. CDH2 joins a group of eight other genes already linked to ARCV, a condition that increases the risk of an abnormal heart beat and sudden death. "This discovery … will permit the diagnosis and possible targeted treatment of heart muscle disease in the future." A South African family with a rare form of hereditary heart disease has helped scientists identify a new gene responsible for sudden-death syndrome, a condition that causes otherwise healthy young people and athletes to go into cardiac arrest. Mayosi's team had since 1996 been puzzling over the cause of a family's hereditary ARCV, which they knewaffected at least five relatives.

Hunch about dogfish leads MDI scientists to potential heart disease breakthrough

Courtesy MDI Biological Laboratory Zebrafish are instrumental in the research. After many years of research, the molecule was developed into the drug MSI-1436, which was then being studied for its potential to treat diabetes. The drug could prove beneficial to people who have had heart attacks or heart disease. One of the key experiments involved injecting MSI-1436 into the bloodstream of the zebrafish to see if it would promote regenerating tissues in a damaged zebrafish heart. Dr. Viravuth Yin, the lead researcher from MDI, said a series of coincidences, combined with years of research on zebrafish and mice, led to the breakthrough.



collected by :Lucy William

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