NFL players' speech may point to brain disease
More than 90 percent of NFL players have brain disease, claims Bennet Omalu, a neuropathologist who had his story about discovering brain trauma and the NFL portrayed by Will Smith in the Concussion. Now a small study is claiming to have found an early link between developing brain disease in NFL players by the simple way that they talk. More and more former NFL players are drawing attention to brain diseases in players. Chronic traumatic encephalopathy (CTE) is a degenerative brain disease that is caused by repeated hits to the head. Within the past few years, more and more retired NFL players have revealed they were diagnosed with degenerative brain diseases, such as dementia and Alzheimer's.
In a new study, researchers have shown that the bacterium responsible for causing TB can suppress the immune system and spread the disease. However, what has not been clear is the role of the pathogen in undermining the immune system to promote spread of the disease. The main route through which people become infected with TB is by inhaling air that contains the TB bacterium, which gets there when a nearby infected person coughs, spits, or sneezes. Thus, the researchers set out to find out more by studying the molecular effects of the TB bacterium on isolated macrophages. They found that the TB bacterium suppresses a signaling pathway called PI3K/AKT/mTORC1 to cause macrophages to release more MMP-1.
collected by :Lucy William