Treatment option for Alzheimer's disease possible : eurekalert

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Treatment option for Alzheimer's disease possible

Treatment option for Alzheimer's disease possible

A research project has shown that an experimental model of Alzheimer's disease can be successfully treated with a commonly used anti-inflammatory drug.A team led by Dr David Brough from The University of Manchester found that the anti-inflammatory drug completely reversed memory loss and brain inflammation in mice.Nearly everybody will at some point in their lives take non-steroidal anti-inflammatory drugs; mefenamic acid, a common Non-Steroidal Anti Inflammatory Drug (NSAID), is routinely used for period pain.The findings are published today in a paper authored by Dr Brough and colleagues, in the respected journal Nature Communications.


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Anti-inflammatory drug shows promise for Alzheimer's disease treatment

Anti-inflammatory drug shows promise for Alzheimer's disease treatment

MANCHESTER, England, Aug. 11 (UPI) -- A common anti-inflammatory drug reversed memory problems similar to Alzheimer's disease in mice, suggesting inflammation makes the disease worse and that treating inflammation may lessen its effects.The non-steroidal anti-inflammatory drug mefenamic acid, marketed as Ponstel, helped fix memory problems in mice, according to researchers at the University of Manchester, though researchers say trials in humans are necessary.Previous studies have shown brain inflammation contributes to the intensification of Alzheimer's disease, which researchers say makes it an obvious target for treatment.Ponstel is a prescription NSAID used to control mild-to-severe pain, specifically pain and blood loss during menstruation.