Health system tapped for national study on disease : detroitnews

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Health system tapped for national study on disease

Health system tapped for national study on disease

Henry Ford Health System has been selected to participate in a national research project studying disease prevention that will poll some 1 million people on lifestyle, environment and genetics.The National Institutes of Health announced Wednesday that it would be adding the Precision Medicine Initiative (PMI) Cohort Program to four regional medical center groups.Selected are Trans-American Consortium for the Health Care Systems Research Network, which includes Henry Ford; California Precision Medicine Consortium; Geisinger Health System; and New England Precision Medicine Consortium.The centers initially will receive a combined total of $5.5 million for recruitment and infrastructure.


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Pancreatic cancer: Sequencing study challenges thinking on disease progression

Pancreatic cancer: Sequencing study challenges thinking on disease progression

Pancreatic cancer is rarely detected in the early stages, as early symptoms are often vague and unrecognized.The result is that by the time diagnosis occurs, the disease is often well advanced, leaving patients with inoperable tumors and very poor prognoses.This tendency for the cancer to appear suddenly has been somewhat of a medical mystery.Now, a genome sequencing study proposes that the disease develops in a different way to that posed in current models.


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U of A researchers to study origin of Leigh's disease

U of A researchers to study origin of Leigh's disease

Researchers at the University of Arkansas and their collaborators will use a $1.4 million grant from the U.S. Department of Defense to study the origin of Leigh's disease, a rare and incurable disease that affects the central nervous system.The goal of the three-year study is to provide a better understanding of the emergence of the mitochondrial mutation that causes the disease, said Shilpa Iyer, assistant professor of biological sciences at the U of A who is leading the study.If successful, the researchers will generate clinical-grade, patient-specific stem cells for drug discovery and transplantation therapies for Leigh's syndrome patients.The team will take skin cells taken from adults suffering from Leigh's disease and re-engineer them into a state that is identical to that of an embryonic stem cell.