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daily : 2016-12-21 & on time : 12:42
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Sanford study explores protein's role in improving survival of ovarian cancer patients
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A Sanford Research lab is studying a protein's role in improving survival in ovarian cancer patients.Findings published in Oncogenesis indicate a higher level of a specific protein correlates with an increased survival rate and decrease in the spreading of cancer cells.Kristi Egland, Ph.D., an associate scientist in the Cancer Biology Research Center at Sanford Research, led the study, which retroactively looked at tumor samples from ovarian cancer patients.Her team noticed that patients with higher levels of the Sushi Domain Containing 2 protein, or SUSD2, experienced less metastasizing of cancer cells and thus survived an average of 18 months longer.
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A 23-year-old bodybuilder is being ravaged by ovarian cancer — and Instagramming it all
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Cheyann Shaw before she was diagnosed with ovarian cancer (left) — and after months of battling it.(Courtesy of Cheyann Shaw/Instagram)Three weeks before her wedding day, Cheyann Shaw uploaded a video to YouTube, a space the fitness fanatic regularly filled with workout clips and health tips.But this time was different: She was now using the social video platform for a more emotional and profound purpose."I'm going to cry," she said in the video, "but — I was told that I have cancer."Shaw has stage 4 low-grade serous ovarian cancer, a rare and slow-growing but stubborn strain that can be resistant to chemotherapy treatments.
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New test could detect ovarian cancer patients who are strongly responding to treatment
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Scientists might be able to quickly predict how ovarian cancer patients are likely to respond to chemotherapy treatment using a simple blood test, according to a Cancer Research UK-funded study published in PLOS Medicine*."This could be a good way to test new types of drugs that target cancer cells specifically and spare patients the side effects from treatments if they are not working." - Professor Peter Johnson, Cancer Research UKIn a study of 40 patients with high grade serous ovarian cancer, the researchers monitored tumour DNA that could be detected in a blood sample taken before each chemotherapy treatment.By measuring the levels of the mutated cancer gene TP53 they found those who responded well to treatment had a rapid fall in the levels of this circulating DNA.The researchers tested levels of this circulating tumour DNA in patients before and after treatment.
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Tumor DNA fragments help predict ovarian cancer outcomes
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A recent study investigated the levels of specific DNA fragments in the blood of ovarian cancer patients.The findings could eventually lead to a blood test that can make accurate predictions about tumor size and disease progression.Detecting DNA fragments from tumors could provide a useful tool in the treatment of cancer.Detecting DNA fragments from tumors could provide a useful tool in the treatment of cancer.
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