CNBC : reported that Exelixis shares jump after team up with Bristol-Myers on cancer trials

Shares of Exelixis jumped 6 percent Monday after the bitotech company announced a clinical development collaboration with Bristol-Myers Squibb. Both compounds are the subject of ongoing, global phase 3 pivotal trials in hepatocellular carcinoma. The company said it is expected to include a phase 3 pivotal trial in first-line renal cell carcinoma, a type of kidney cancer, with additional trials planned in bladder cancer, hepatocellular carcinoma, a form of liver cancer, and potentially other tumor types. Cabometyx and Opdivo have both received approval in the U.S. and European Union for specific uses in previous treated renal cell carcinoma. With Monday's gains, Exelixis is up more than 50 percent year to date.

Cold Spring Harbor team finds clues to cancer treatment

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Bristol, Roche team up with Exelixis on cancer trials

Bristol-Myers, Roche and Merck & Co, are the three heavyweights in that class, and have made it clear in recent months their intent to lock down more collaborations. Exelixis and Bristol-Myers expect to initiate other trials testing their combo therapy in a variety of cancers, including bladder and liver. Dive Insight:The deals come as no surprise given how combination therapies are on the rise inthe immuno-oncology space, particularly among checkpoint inhibitor drugs. Dive Brief:West coast biotech Exelixis has entered two new partnerships to test its cancer medication in combination with Bristol-Myers Squibb and Roche's competing checkpoint inhibitors. Phase 1b, trial of Those initial trials are also serving as the springboard for additional investigations.



collected by :Lucy William

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