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Monday, March 13, 2017

Antidepressants 'STOP prostate cancer spreading to the bones stat : The Sun

"When we reduced this enzyme expression in prostate Cancer cells, we found a lower Prostate cancer bone metastasis," Dr Wu said. Getty Images 2 Scientists believe antidepressants could help in the fight against prostate cancerIn nine out of 10 fatal cases of prostate cancer, the disease spreads to the bones. He added: "To be sure, there have been no clinical studies reporting a lower risk of prostate cancer in people currently taking antidepressants. "We are an incredibly long way off knowing whether drugs like this could put a stop to prostate cancer cells spreading to the bone in reality," he said. Prostate cancer is the most common form of the disease in men, and more than 47,000 cases are diagnosed every year in the UK – that's 130 men a day, according to Prostate Cancer UK.



Antidepressants 'STOP prostate cancer spreading to the bones
After skin Cancer, prostate cancer is most common cancer among men in the United States and the third leading cause of cancer death. MAOA enzyme helps prostate cancer cells spread to boneThe researchers came to their findings by introducing human prostate cancer cell lines into mice and analyzing MAOA activity. Researchers suggest that antidepressants that block the enzyme MAOA could reduce the spread of prostate cancer cells to the bone. According to the American Cancer Society, there will be 161,360 new cases of prostate cancer diagnosed in 2017, and more than 26,000 men will die from the disease. When prostate cancer cells spread to other body parts - a process known as metastasis - the bone is the normally the first area affected.

Could antidepressants stop prostate cancer from spreading?
Like many cancers, prostate cancer rarely stays put in the organ it is named for. … current therapies have very limited or no effectiveness for prostate cancer patients who develop metastatic bone tumors. Even more notably, "current therapies have very limited or no effectiveness for prostate cancer patients who develop metastatic bone tumors," he said. The disease has a special knack for spreading into bones, a painful and lethal development that affects 90 percent of patients who die of prostate cancer. In his study, Wu also found that a drug similar to ones used in antidepressants was able to disrupt the MAOA enzyme, meaning it could be used to prevent prostate cancer from spreading to the bones.



collected by :Lucy William

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