Obesity, central obesity increase precocious puberty risk quoting : healio

Central Obesity was found in 38.58% of boys and 29.42% of girls with precocious puberty, and central obesity had a similar effect on precocious puberty compared with obesity (boys, OR = 2.1; 95% CI, 1.46-3.03; girls, OR = 5.4; 95% CI, 4.1-7.12). We aimed to investigate the relationship between precocious puberty and obesity as well as central obesity. The risk for precocious puberty may be increased with childhood obesity and/or central obesity; the risk is more pronounced in girls than boys, according to findings from China published in BMJ Open. Boys had a higher prevalence of obesity (boys, 18.61% vs. girls, 5.63%) and central obesity (28.65% vs. 13.09%) compared with girls (P < .001). Obesity is reported to be closely relevant to early sexual development but the relationship between sexual precocity and obesity or central obesity is still inconsistent, especially in boys.




Within the cohort, there were 654 incident cases of type 2 diabetes and 1,318 incident cases of type 1 diabetes occurring between 1994 and 2013. Researchers did not observe any association between obesity and incident type 1 diabetes. In nested, case-control analysis, researchers found that children with obesity made up 47% of type 2 diabetes cases and had approximately four times the risk for incident type 2 diabetes vs. those with a normal BMI (OR = 3.7; 95% CI, 3.1-4.6). Cases of type 2 diabetes per 100,000 persons per year increased from 6.4 in 1994-1998 to 33.2 in 2009-2013. Compared with children with normal weight, children with obesity are four times more likely to develop incident type 2 diabetes before reaching adulthood, according to findings published in the Journal of the Endocrine Society.

Central obesity may increase mortality risk from cardiovascular disease

Meanwhile, overweight adults with central obesity had an 11 percent increased mortality risk compared with overweight adults who did not have central obesity. Overweight adults with central obesity had an increased risk of mortality compared with counterparts without central obesity, according to a survey analysis. In addition, obese adults with central obesity had a 27 percent increased mortality risk compared with obese adults who did not have central obesity. Further, all participants were central obesity had an increased mortality risk from cardiovascular disease compared with the reference group. Normal weight and obese participants with central obesity were the only groups at an increased mortality risk compared with normal weight participants without central obesity, which was the reference group.


collected by :Lucy William

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