Benefits of metformin may involve gut bacteria quoting : diabetes

Both groups were pDiabetes and insuranceut on a low-calorie diet Researchers discovered the bacteria found in the gut changed significantly in those who had been taking metformin. The human stool samples were taken before and after metformin treatment and the mice had been put on a high-calorie diet. "Now researchers think the results of the study might indicate that people with type 2 diabetes might be able to control their condition better by being mindful of foods which might help promote good gut bacteria. "Our findings provide support for the notion that altered gut microbiota mediates some of metformin's antidiabetic effects. The fecal transplant is thought to help pass good bacteria from a healthy person to someone who is unwell.Excrement taken from those who had been taking the metformin seemed to help control blood glucose levels in the mice.




Scimat/Science Photo LibraryThe most successful treatment for type 2 diabetes may work by changing the makeup of gut bacteria. The drug is generally believed to work by reducing the amount of glucose made in the liver, which would in turn lower blood sugar levels. During the study period, the collection of gut bacteria changed much more dramatically in those taking metformin. Fredrik Bäckhed at the University of Gothenburg, Sweden, and José Manuel Fernàndez-Real at the University of Girona, Spain, wondered if gut bacteria might play a role in the drug's action. Together, the results suggest that metformin at least partly works by encouraging the growth of gut bacteria such as Akkermansia, which can influence blood sugar levels.

Common diabetes drug may work by changing gut bacteria

The most common medication for type 2 diabetes may work by changing the composition of the bacteria in the gut, a study reveals. Researchers discovered that certain strains of bacteria - which can reduce blood sugar levels - grew faster in the presence of the drug metformin. Together, the findings of these studies suggest that metformin at least partly works by encouraging the growth of gut bacteria such as akkermansia. The mice given this saw an improvement in their glucose tolerance - a measure of how well animals can control blood sugar levels. Metformin is believed to lower blood sugar levels primarily by reducing the amount of glucose produced and released by the liver.


collected by :Lucy William

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